The $100B Paradox: Why the Largest Company in Healthcare Hasn’t Been Built Yet

Originally published in Second Opinion, a newsletter for healthcare founders, operators, and investors.

If the United States’ healthcare sector were its own country, it would be the third largest economy in the world. By any rule of capitalism, a market that size should have minted a titan. Software gave us multiple trillion dollar platforms. Retail, search, advertising, even payments each produced a generational tech giant. And yet healthcare has not produced a single $100 billion healthtech company. 

Why? The short answer is that technology, for the most part, hasn’t actually created value in healthcare. It shuffled it, bureaucratized it, and in many cases destroyed it. The longer answer is that might all be changing now.

Continue reading

The Future of Substance Use Care Is AI-Native

Repost from LinkedIn.

A clinician finishes a 50-minute session. The member leaves. The clinician opens their laptop and begins the second session: 45 minutes of documentation. They reconstruct the conversation from memory, translate it into billing codes, fill templates designed for auditors, and hunt through tabs to cross-reference previous notes. Then they move to the next patient.

This happens six times a day. More time documenting than treating. It’s not an edge case. It’s the norm.

Show me the incentive and I’ll show you the outcome

Electronic Health Records (EHRs) were never built for care. They were built for billing. The systems designed in the 1990s now stand between clinicians and patients, optimized to capture every action, convert it into codes, and generate revenue. Clinical workflows became data-entry workflows – serving payers, not patients.

This design misalignment produces predictable distortions. Providers maximize billable sessions because income scales with time spent, not outcomes achieved. The financial incentive isn’t to solve the problem efficiently. It’s to extend the engagement. In that sense, the system isn’t broken, it’s working exactly as intended. The flaw lies in what it was designed to optimize.

The consequences are staggering. The U.S. spends roughly $50 billion each year on substance use disorder (SUD) treatment, yet reaches only about 10% of those in need. The remaining 90%, generate an estimated $135 billion in preventable downstream costs, from ER visits to comorbidity complications to inpatient care.

We’re spending more and helping fewer. The bottleneck isn’t money. It’s infrastructure built around the wrong objective function.

Continue reading

Lessons Learned Scaling A Mission-Driven Startup

Note: This post is based on a presentation I gave at Web Summit 2021 and was later compiled in an article published in Forbes on Aug 22, 2022.

At the age of 14, when I started my first business, the notion that it was a business didn’t compute. Sure, there were ads to sell to pay for server costs and hire programmers, but the label of “business” sounded like a betrayal of our mission-driven values. At age 30 and working on my third startup, being mission-driven and for-profit no longer seems paradoxical.

Over the years, I’ve learned three crucial lessons in scaling a mission-driven business:

1. Don’t make it about the short term.

Many people—even some investors—think that mission-driven means nonprofit. The reality couldn’t be further from the truth. The most profitable companies are mission-driven, but their purpose goes beyond Wall Street’s short-term quarterly expectations.

Continue reading

In Defence of the Naïve Founder 

One of my most memorable moments from medical school was during my rotation in a psychiatric hospital. Unlike traditional medicine, you’re unlikely to figure out what is going on by sticking the patient with needles. Instead you learn to listen for inconsistencies that might indicate a delusion or hallucination.

On one occasion, I was taking a medical history from a well-kept man on a psychiatric ward who wouldn’t have looked out of place in a law firm or investment bank. That was until he started to describe, in all seriousness, that “agents” had been tailing him for weeks. Apparently, he had been assigned a top secret mission to penetrate a cult and was on the verge of uncovering a major conspiracy.

While delusions of this kind sound impressive, it wouldn’t be unusual to hear similarly grandiose stories from a startup founder.

Self-confidence to the point of delusional seems to be a common trait amongst successful founders. Later stage founders often admit to having no idea what they were getting themselves into when they first started their company. 

Continue reading

The Art of Deciding

“To take away a man’s freedom of choice, even his freedom to make the wrong choice, is to manipulate him as though he were a puppet and not a person.”

Madeline L’Engle

The ability to decide is at the heart of what it means to be human. After all, history started with the hasty decision to take a bite of the forbidden fruit. And, like Adam most of us make consequential decisions with little to no thought. 

Decision-making is not taught in schools and rarely discussed in leadership circles. There are countless books on how to be more productive, yet relatively few on how to decide. In fact, it wasn’t until recently that academia moved away from the ludicrous idea that humans are rational beings and decision-making gained the fancy moniker, “behavioral economics”, signifying its elevation as a formal field of science, thanks to the work of prominent academics such as Daniel Kahneman and Richard Thaler.

Continue reading

The Most Important Thing I Learned During Y Combinator

Tuesday “dinners” were a big part of the YC experience. An opportunity to take a break from the grind, share notes and compare progress with fellow batchmates. 

But the highlight of the evening was always an off-the-record talk by an experienced startup founder who was, more often than not, also YC alumnus. During my batch (Winter 2018), we had the opportunity to hear from no less than Drew Houston (Dropbox), Brian Chesky and Joe Gebbia (Airbnb), and Emmit Shear and Justin Kan (Twitch), to name a few. 

The talk that I’ve thought back to the most was Sam Altman, former President of YC’s, opening address on “How to Succeed”.

Continue reading

The UK and Creating an Innovative Health-Tech Culture

Imagine a near-infinite improbability drive that takes common, raw materials and transforms them into a conveyor belt of wealth-creating products and services. 

Once you owed such a device, you would do everything you could to preserve and protect it. The improbability drive I refer to is “innovation” and the UK was once good at it for healthcare. 

From penicillin to the smallpox vaccine, the UK has a long history of punching above its weight in the field of healthcare innovation. Unfortunately, we have ceded that lead, in part, due to an increasingly hostile culture towards health-tech entrepreneurs.

Here’s why. Innovation is the result of trial and error by tinkerers, often preceding our scientific understanding. It proliferates in decentralized environments where people are free to think, experiment and speculate. It is almost always bottom-up rather than top-down.

The first challenge is the UK’s centralized approach to healthcare that optimizes for low cost at the expense of innovation and spends 20% less per capita on healthcare than the OECD average.

A lack of willingness to invest in innovative health-tech projects coupled with bureaucratic decision-making has created an environment of limited opportunity for new upstarts. The result has been a brain drain of the best and brightest health-tech entrepreneurs migrating to more innovation-friendly markets.

Continue reading